论文部分内容阅读
目的探讨葛根素注射液致溶血性贫血死亡的临床特点及发生规律,为临床合理使用葛根素注射液提供参考。方法对1998年~2007年国内文献报道的葛根素注射液致溶血性贫血死亡9例病例进行统计和分析。结果9例病例中男性8例,女性1例,年龄均在60岁以上。患者用量剂量为200~600mg,每日1次;均是使用葛根素注射液7~12d后死亡;其中7例使用葛根素注射液过程中发现有溶血症状,但未及时识别而继续用药,最终导致溶血性贫血死亡。1例有葛根素注射液用药史,在第2次用药过程中死亡。结论葛根素注射液致溶血性贫血死亡属于极为罕见的不良反应,应引起医务人员的高度重视。
Objective To investigate the clinical characteristics and occurrence of death caused by puerarin injection and provide a reference for the rational use of puerarin injection in clinic. Methods Nine cases of hemolytic anemia caused by puerarin injection reported in domestic literature from 1998 to 2007 were statistically analyzed. Results Among 9 cases, 8 males and 1 females were aged above 60 years old. The patient dosage was 200-600mg, once a day; all were using puerarin injection after 7 ~ 12d and died; among them, 7 cases were found to have hemolytic symptoms in the course of puerarin injection, Lead to death from hemolytic anemia. 1 case of puerarin injection medication history, died during the second medication. Conclusion The death of haemolytic anemia caused by puerarin injection belongs to a very rare adverse reaction, which should be paid great attention to by medical staffs.