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目的探讨异种脱细胞真皮基质(ADM)包扎治疗烧烫伤Ⅱ度创面的临床效果。方法随机采用ADM包扎治疗(观察组)和使用磺胺嘧啶银乳膏包扎治疗(对照组)的烧烫伤Ⅱ度创面各50例。比较两组在换药后疼痛、换药次数、预后瘢痕增生等方面的差异。结果观察组0~Ⅰ级疼痛入院时22例(44%),治疗后48例(96%),差异具有统计学意义(P<0.01);对照组0~Ⅰ级疼痛入院时23例(46%),治疗后20例(40%),差异无统计学意义(P>0.05)。两组治疗后0~Ⅰ级疼痛率比较,差异有统计学意义(P<0.01)。观察组患者创面愈合后皮肤颜色比对照组颜色更浅、弹性更好。半年后创面瘢痕形成有明显差异(P<0.01)。结论 ADM治疗烧烫伤Ⅱ度创面具有止痛快、促进创面愈合,减少瘢痕增生,减轻患者痛苦,减少医生劳动量等优点。
Objective To investigate the clinical efficacy of xenografted acellular dermal matrix (ADM) dressing in the treatment of burn wound Ⅱ degree wounds. Methods Randomly treated with ADM banding (observation group) and sulfadiazine silver cream dressing (control group), 50 cases were treated with burn wound Ⅱ degree. The differences between the two groups in terms of pain after dressing change, frequency of dressings and prognosis of scar were compared. Results In the observation group, 22 patients (44%) had grade 0 ~ Ⅰ pain at admission and 48 patients (96%) after treatment, the difference was statistically significant (P <0.01); in the control group, 0 ~ %), 20 cases (40%) after treatment, the difference was not statistically significant (P> 0.05). The pain rates of 0 ~ Ⅰ group after treatment were significantly different between the two groups (P <0.01). In the observation group, the skin color of the wound healing was lighter and the color of the skin was better than the control group. Half a year after the wound scar formation were significantly different (P <0.01). Conclusion ADM treatment of burns and burn wounds with Ⅱ degree fast pain relief, promote wound healing, reduce scar hyperplasia, reduce patient suffering, reduce the workload of doctors and so on.