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目的探讨足部恶性黑色素瘤的临床表现、诊断与治疗。方法回顾性分析笔者所在科室2000年1月～2010年5月收治的37例足部恶性黑色素瘤患者的临床资料。结果所有患者均经病理证实为恶性黑色素瘤。1例放弃治疗,36例确诊后接受了外科手术治疗,其中单独手术4例,手术+化疗6例,手术+免疫治疗4例,手术+放疗5例,手术+化疗+免疫治疗15例,手术+化疗+免疫治疗+放疗2例。37例随访3个月～7年。14例患者于1～25个月内死亡,其余患者存活。结论目前,足部恶性黑色素瘤仍是不能根治的疾病,但经过正规手术,辅助化疗、免疫、放射治疗,有助于患者恢复足部良好功能,提高患者生存质量。
Objective To investigate the clinical manifestations, diagnosis and treatment of foot malignant melanoma. Methods The clinical data of 37 patients with malignant melanoma of the foot admitted to our department from January 2000 to May 2010 were retrospectively analyzed. Results All patients were pathologically confirmed as malignant melanoma. One patient gave up treatment and 36 patients were diagnosed with surgical treatment. Among them, 4 were surgery alone, 6 were surgery and chemotherapy, 4 were surgery and immunotherapy, 5 were surgery and radiotherapy, 15 were surgery and chemotherapy and 15 were immunotherapy, + Chemotherapy + immunotherapy + radiotherapy in 2 cases. 37 cases were followed up for 3 months to 7 years. Fourteen patients died within 1 to 25 months and the remaining survived. Conclusion At present, foot malignant melanoma is still an incurable disease, but after formal surgery, adjuvant chemotherapy, immunotherapy and radiation therapy can help patients recover the good function of foot and improve the quality of life of patients.