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目的研究小麦纤维素颗粒与双歧杆菌三联活菌散联合治疗小儿功能性便秘的临床作用。方法随机从本院接诊的功能性便秘患儿中抽取50例作为观察对象,将其随机分为对照组和观察组,每组25例。对照组采用单纯小麦纤维素颗粒治疗,观察组采用小麦纤维素颗粒与双歧杆菌三联活菌散联合的治疗方法。观察两组患儿的大便性状和大便时的情况,分别评价两组患儿的治疗效果。结果经过临床干预后,两组患儿的症状均有好转,但观察组患儿的治疗效果相比对照组更加明显,两组比较差异具有统计学意义(P<0.05)。经过15 d的临床干预后,观察组患儿的治疗总有效率为88.0%,对照组为48.0%,观察组患儿每周的排便次数逐渐正常化,大便性状有了明显改善,治疗周期与对照组相比较短。两组患儿在治疗期间均无不良反应出现。结论通过对两种治疗方法的治疗结果比较,小麦纤维素颗粒与双歧杆菌三联活菌散联合比单纯小麦纤维素颗粒治疗小儿功能性便秘的疗效更加显著。
Objective To study the clinical effect of combination of wheat cellulose granules and bifidobacterium triple active bacterial powder in the treatment of children with functional constipation. Methods Fifty patients with functional constipation admitted from our hospital were randomly divided into control group and observation group, with 25 cases in each group. The control group was treated with pure wheat cellulose granules. The observation group was treated with the combination of wheat cellulose granules and Bifidobacterium triple viable powder. The stools and defecation of the two groups were observed, and the therapeutic effects of the two groups were evaluated respectively. Results After the clinical intervention, the symptoms of both groups improved, but the treatment effect of the observation group was more obvious than that of the control group. The difference between the two groups was statistically significant (P <0.05). After 15 days of clinical intervention, the total effective rate was 88.0% in the observation group and 48.0% in the control group. The number of bowel movements in the observation group was gradually normalized each week, and the stool performance was significantly improved. The treatment period The control group is shorter. No adverse reactions occurred in both groups during treatment. Conclusion By comparing the results of the two treatment methods, the combination of wheat cellulose granules and Bifidobacterium triple viable powder is more effective than pure wheat cellulose granules in the treatment of children with functional constipation.