涂敷型直链淀粉手性固定相的制备及对外消旋体农药喹禾灵的分离研究

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Amylose tris(3,5 dimethphenylcarbamate) was synthesized and used as the chiral stationary phase upon adsorption over silica gel. This stationary phase offered a practically useful chiral column with a high enantiomer separability. Amylose was allowed to react with an excess of 3,5 dimethphenylcarbamate in pyridine for 48h. The obtained carbamate was dissolved and adsorbed on silica gel which has been treated with 3 aminopropyltriethoxysilane. The weight ratio of the carbamate to the silica gel was 0.45/2.55. The quizalofop was resoluted on amylose tris(3,5 dimethphenylcarbamate) chiral stationary phase. Separation was carried out with a hexane/2 propanol mixture at a flow rate of 0.5 mL·min -1 at room temperature. The effects of 2 propanol concentration on the retention and resolution had been investigated. Amylose tris (3,5 dimethphenylcarbamate) was synthesized and used as the chiral stationary phase upon adsorption over silica gel. Amylose was allowed to react with an excess of 3,5 The weight ratio of the carbamate to the silica gel was 0.45 / 2.55. The weight ratio of the carbamate to the silica gel was 0.45 / 2.55. The quizalofop was resoluted on amylose tris (3,5 dimethphenylcarbamate) chiral stationary phase. Separation was carried out with a hexane / 2 propanol mixture at a flow rate of 0.5 mL · min -1 at room temperature. The effects of 2 propanol concentration on the retention and resolution had been investigated.
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