病变局限于肺内的非小细胞肺癌单纯手术能治愈,转移性病变手术无好处。为了提高切除率及生存率,Memorial Sloan-Kettering癌症中心在1984年1月～1989年11月间对73例经组织学证实,临床检查发现同侧纵隔淋巴结转移的非小细胞肺癌病人采用以顺铂为基础的药物化疗。治疗前Kar-nofsky>70占83％。中位年龄53岁(31～71岁)。腺癌占55％,上皮癌占31％,大细胞癌占14％。T_1病变占11％,T_263％,T_326％。全部病人均为ⅢA Non-small cell lung cancer with lesions confined to the lungs can be cured by surgery alone, and metastatic lesions have no benefit. In order to improve the resection rate and survival rate, the Memorial Sloan-Kettering Cancer Center used 73 cases of non-small cell lung cancer patients who were identified by histology from January 1984 to November 1989 on clinical examinations and found that they had ipsilateral mediastinal lymph node metastases. Platinum-based chemotherapy. Kar-nofsky >70 accounted for 83% before treatment. The median age is 53 years (31-71 years old). Adenocarcinomas account for 55%, epithelial cancers 31%, and large cell carcinomas 14%. T_1 lesions accounted for 11%, T_263%, and T_326%. All patients are IIIA