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目的观察复方野马追胶囊对呼吸道合胞病毒(RSV)感染及炎性因子IL-8释放的抑制作用。方法采用细胞病变(CPE)观察和活细胞染色方法,观察复方野马追胶囊对呼吸道合胞病毒感染细胞的保护。同时,通过ELISA法测定培养上清IL-8的变化。结果复方野马追胶囊对呼吸道合胞病毒感染有抑制作用,其中以治疗法效果最为明显。同时该药对呼吸道合胞病毒感染后引起的IL-8释放也有明显抑制作用。结论复方野马追胶囊具有明显的体外抗呼吸道合胞病毒感染、降低感染后气道炎症因子释放的作用。
Objective To observe the inhibitory effect of Fumangmaqian capsule on respiratory syncytial virus (RSV) infection and IL-8 release. Methods The cytopathic effect (CPE) observation and viable cell staining were used to observe the protective effect of Fumangqian Capsule on respiratory syncytial virus infected cells. Meanwhile, the change of IL-8 in culture supernatant was measured by ELISA. The results of the compound mustang chase capsules on respiratory syncytial virus infection inhibited, of which the treatment effect is most obvious. At the same time the drug on respiratory syncytial virus infection caused IL-8 release also had a significant inhibitory effect. Conclusion Fumangmao chang capsule has significant anti-respiratory syncytial virus infection in vitro, reducing the release of airway inflammatory cytokines.