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为了探讨液基薄层细胞学技术(thin prep cytologic test,TCT)及阴道镜检查对子宫颈病变的诊断价值,收集6521例患者及健康体检者,进行TCT检测,TCT阳性者行阴道镜检查及活检。TCT异常者688例(10.55%),TCT和阴道镜对低度鳞状上皮内瘤变(LSIL)的检出率分别为63.96%(158/247)和70.04%(173/247),高度鳞状上皮内瘤变(HSIL)为73.03%(65/89)和84.27%(75/89),宫颈浸润癌(CC)为81.82%(27/33)和96.97%(32/33)。初步研究结果提示,TCT筛查是诊断宫颈病变的重要方法,配合阴道镜下活检,能提高子宫颈癌前病变和宫颈早期浸润癌检出率,具有重要的临床意义。
To investigate the diagnostic value of thin prep cytologic test (TCT) and colposcopy on cervical lesions, 6521 patients and healthy subjects were collected for TCT test, colposcopy-positive TCT test and Biopsy. 688 (10.55%) patients with TCT abnormalities and 63.96% (158/247) and 70.04% (173/247) patients with low-grade squamous intraepithelial neoplasia (TCIL) and colposcopy respectively The rates of HSIL were 73.03% (65/89) and 84.27% (75/89) respectively, and those of cervical invasive carcinoma (CC) were 81.82% (27/33) and 96.97% (32/33). Preliminary results suggest that TCT screening is an important method of diagnosis of cervical lesions, with colposcopy biopsy can increase the rate of cervical precancerous lesions and early invasive carcinoma of the cervix, has important clinical significance.