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进行性多灶性白质脑病正如其名称所示是一种进行性中枢神经系统多发性脱鞘病,其神经元相对的完整、常伴发于免疫缺陷疾病的过程中,一般常需脑组织活检才能确诊,预后相当差,常于发病后3~20个月死亡.作者报告一例本病患者,经过多方面检查在其脑脊液细胞中找到猿病毒40(SV40)抗原,并作了脑组织活检,用阿糖胞苷治疗获良效.病人男性,32岁,因一周来进行性步态不稳,共济失调,穿衣困难入院,既往10年内因治疗郝杰金氏病用过长春
Progressive multifocal leukoencephalopathy, as the name implies, is a progressive central nervous system multiple dehiscence disease with relatively intact neurons, often associated with immunodeficient diseases, and often requires brain biopsies Can be diagnosed, the prognosis is quite poor, often died in 3 to 20 months after onset.A report of a patient with this disease, after many checks in its cerebrospinal fluid cells to find simian virus 40 (SV40) antigen and brain biopsy, Treatment with cytarabine was good. The patient, male, 32 years old, had one week of unstable sexual gait, ataxia and difficulty in dressing and was hospitalized in the past 10 years due to the treatment of Hodgkin’s disease in Changchun