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目的:观察胃溃疡患者给予牙周基础治疗后胃内幽门螺杆菌(Hp)清除率变化,探讨牙周基础治疗对胃溃疡治疗的辅助效果;方法:胃溃疡病伴有牙周疾病的患者88例随机分为2组,对照组44例给予常规三联药物治疗,观察组44例在对照组基础上再给予牙周基础治疗,疗程1个月。治疗后1,3,6,12个月,检测牙周及胃内Hp变化,比较两组Hp根除率。结果:治疗后3,6,12个月,观察组Hp根除率均显著高于对照组(P<0.05)。结论:对于有牙周疾患的胃溃疡Hp感染患者,在三联治疗的基础上辅助牙周基础治疗,能明显提高Hp根除率。
OBJECTIVE: To observe the change of Helicobacter pylori (Hp) clearance rate in gastric ulcer patients after basic periodontal treatment and to explore the effect of basic periodontal treatment on the treatment of gastric ulcer. Methods: Patients with gastric ulcer and periodontal disease 88 Cases were randomly divided into two groups, the control group of 44 patients given conventional triple drug treatment, the observation group of 44 patients in the control group based on the basic periodontal treatment, the course of 1 month. At 1, 3, 6 and 12 months after treatment, the changes of Hp in periodontal and gastric tissues were detected, and the eradication rate of Hp in both groups was compared. Results: At 3, 6 and 12 months after treatment, the Hp eradication rate in observation group was significantly higher than that in control group (P <0.05). Conclusion: For patients with Hp infection of gastric ulcer with periodontal disease, basic periodontal treatment based on triple therapy can significantly improve the Hp eradication rate.