Detection of HIV-1 antigen based on magnetic tunnel junction sensors

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We report a p24 (HIV disease biomarker) detection assay using an MgO-based magnetic tunnel junction (MTJ) sensor and 20-nm magnetic nanoparticles.The MTJ array sensor with sensing area of 890 × 890 μm2 possessing a sensitivity of 1.39%/Oe was used to detect p24 antigens.It is demonstrated that the p24 antigens could be detected at a concentration of 0.01 μg/ml.The development of bio-detection systems based on magnetic tunnel junction sensors with high-sensitivity will greatly benefit the early diagnosis of HIV.
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