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目的:探讨尿微量白蛋白尿肌酐比值与急性脑梗死患者颅内外动脉病变情况的关系。方法:筛选急性动脉粥样硬化血栓性脑梗死71例为研究对象,测定尿微量白蛋白尿肌酐比值(UACR),并行磁共振血管成像(头MRA)3.0T检查及颈动脉内膜中层厚度(IMT)的测量,比较UACR阳性患者和UACR阴性患者颅内外动脉的病变情况。结果:UACR阳性患者较UACR阴性患者的颅内动脉多发狭窄率及颈动脉内膜中层厚度有统计学差异。结论:UACR阳性脑动脉多发狭窄率更高,颈动脉硬化程度更重。
Objective: To investigate the relationship between urinary albuminuria creatinine ratio and extracranial arterial disease in patients with acute cerebral infarction. Methods: Seventy-one patients with acute atherothrombotic cerebral infarction were screened for UACR, 3.0T examination of MRA and 3.0T of carotid intima-media thickness ( IMT) were measured to compare the intracranial and extracranial arterial lesions in UACR-positive patients and UACR-negative patients. Results: UACR positive patients than UACR negative patients with multiple intracranial stenosis rate and carotid artery intima-media thickness were statistically different. Conclusion: The prevalence of multiple stenosis of UACR positive cerebral arteries is higher and carotid atherosclerosis is more serious.