强心利尿剂氨茶碱(乙二胺茶碱)与抗炎剂强的松(在体内生成强的松龙)的药物相互作用于1978年曾报道过3例。此报告说强的松龙因并用氨茶碱,其生物利用度降低了48%,另一方面由于并用强的松,茶碱生物半衰期以及生物利用度分别降低了27%和53%。因此 Anderson 博士对氨茶碱及强的松分别口服时与合用时的各自生物利用度的 A cardiac drug diuretic aminophylline (ethylenediamine theophylline) and anti-inflammatory agent prednisone (in vivo production of prednisolone) drug interactions were reported in 1978, three cases. The report said that prednisolone with aminophylline and its bioavailability reduced by 48%, on the other hand with prednisone, theophylline biological half-life and bioavailability were reduced by 27% and 53%. Therefore, Dr. Anderson, aminophylline and prednisone were oral and combined with the respective bioavailability