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本文采用高分辨染色体显带技术研究了1例 M_2型急非淋患者的白血病细胞,发现一种新的、未曾报道过的染色体异常 t(3;21)(p14;q22)。患者系17岁白种女性,因疲劳,发热伴牙龈出血2个月于1982年入院,外周血三系细胞低下,血片中60%的白细胞为幼稚细胞,骨髓中有核细胞高度增
In this study, we investigated the leukemia cells of a patient with M_2 acute non-lymphoid leprosy by high resolution chromosome banding technique and found a new and unrecorded chromosomal abnormality t (3; 21) (p14; q22). The patient was a 17-year-old Caucasian female. Her fatigue, fever and gingival bleeding were admitted to hospital for two months in 1982. The peripheral blood mononuclear cells were poorly expressed. 60% of leukocytes in the blood film were immature cells,