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目的探讨选择性动脉介入溶栓治疗椎基底动脉血栓形成的疗效。方法自2005年02月～2007年3月收治6例椎基底动脉血栓形成病人,经脑血管造影证实为椎基底动脉闭塞,行超选局部动脉溶栓治疗,5例行机械性破栓和局部动脉溶栓治疗,其中有3例基底动脉狭窄病人行球囊及支架成形术;1例直接闭塞动脉近端溶栓治疗。结果5例椎基底动脉再通,术终意识障碍明显改善4例,其中出院时恢复正常2例,轻度残疾1例,中度残疾1例;1例术后颅内出血,出院时达中度残疾;1例溶栓后未通者,术后死亡。结论介入溶栓治疗是椎基底动脉血栓形成一种有效的治疗方法,它可以提高血管再通率,改善预后。
Objective To investigate the therapeutic effect of selective arterial thrombolysis on vertebrobasilar thrombosis. Methods Six patients with vertebrobasilar thrombosis were admitted from February 2005 to March 2007. The patients were diagnosed as vertebrobasilar artery occlusion by cerebral angiography and were treated with superselective local arterial thrombolysis. Five patients underwent mechanical thrombolysis and local Arterial thrombolysis, including 3 cases of patients with basilar artery stenosis and balloon angioplasty; 1 case of immediate occlusion of the proximal thrombolysis artery. Results In 5 cases, the vertebrobasilar artery recanalization was improved in 4 cases, including 2 cases of normal discharge, 1 case of mild disability, 1 case of moderate disability, 1 case of postoperative intracranial hemorrhage, Disability; 1 case failed after thrombolytic therapy, died after surgery. Conclusion Interventional thrombolytic therapy is an effective treatment for vertebrobasilar thrombosis, which can improve the recanalization rate and improve the prognosis.