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重组FN多肽CH50可以显著促进巨噬细胞产生NO的能力、增强其细胞毒作用。CH50多肽可与IFNγ协同作用,进一步促进巨噬细胞产生NO的能力。体内实验亦表明,CH50多肽可以抑制肿瘤细胞在体内生长,与IFNγ协同作用则可获得更佳效果
Recombinant FN polypeptide CH50 can significantly promote macrophage NO production and enhance its cytotoxicity. CH50 polypeptide synergistic effect with IFN γ, to further promote the ability of macrophages to produce NO. In vivo experiments also show that, CH50 polypeptide can inhibit the growth of tumor cells in vivo, and synergistic effect with IFN γ can get better results