Isaac曾报告持续异常肌肉活动的特征是:自发的局部肌肉有节律性收缩,偶见疼痛、肌肉强直和出汗过度。已证明异常肌肉活动由周围神经引起,但至今病因不明。本文报告一例药物阻断和糖皮质激素治疗的效果。 患者女性,20岁。既往身体健康。第三次妊娠第26周出现胸部肌肉局限性持续收缩,睡眠时不消失。紧张和寒冷其收缩幅度和频率增加,无肌痛和强直。体检及神经系统检查除异常肌肉活动外,未发现异常。血液补体、抗核抗体、抗磷脂抗体及CSF检 Isaac has reported sustained abnormal muscle activity is characterized by: spontaneous local muscle rhythmic contraction, occasionally pain, muscle rigidity and excessive sweating. Abnormal muscle activity has been shown to be caused by peripheral nerves, but so far the cause is unknown. This article reports the effects of a drug block and glucocorticoid treatment. Patient female, 20 years old. In the past, good health. Thirty-sixth weeks of the third pregnancy with persistent muscle contraction limitations, does not disappear when sleeping. Tension and cold increase its contraction rate and frequency, no muscle pain and stiffness. Physical examination and neurological examination In addition to abnormal muscle activity, no abnormalities were found. Blood complement, anti-nuclear antibodies, anti-phospholipid antibodies and CSF testing