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检测了３０例慢性活动性肝炎患者、３０例肝硬化患者、３０例亚临床肝性脑病患者血清中的铜、锌含量，并与正常对照组进行比较分析，探讨了微量元素铜、锌的血清含量改变及其影响因素，分析其临床意义．结果表明体内的铜锌含量与肝脏功能有密切的关系．在慢性活动性肝炎时，虽然肝脏功能有一定的损害，但由于肝脏的代偿能力强，铜、锌含量仍可保持在正常水平，而在肝硬化、亚临床肝性脑病时，铜锌明显降低，而铜锌含量的降低又导致机体的许多酶活性的降低，使机体的功能进一步衰退．因此在出现肝脏疾患时，测定血中铜、锌含量将有助于判断病情的发展及对临床治疗有一定的帮助。
The levels of copper and zinc in sera of 30 patients with chronic active hepatitis, 30 patients with cirrhosis and 30 patients with subclinical hepatic encephalopathy were detected and compared with the normal control group. The serums of trace elements copper and zinc Content changes and its influencing factors, analyze its clinical significance. The results show that the body’s copper and zinc content and liver function are closely related. In chronic active hepatitis, although liver function has some damage, but due to the compensatory ability of the liver, copper, zinc content can still be maintained at normal levels, and in cirrhosis, subclinical hepatic encephalopathy, copper and zinc significantly Lower, while the reduction of copper and zinc levels in turn lead to the reduction of many of the body’s enzyme activity, the body’s function further decline. Therefore, in the presence of liver disease, the determination of blood copper, zinc content will help determine the progression of the disease and clinical treatment have some help.