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我们以地高辛标记癌基因c－erbB－2和c－mycDNA探针，采用细胞原位杂交方法检测上消化道肿瘤组织中两种癌基因的扩增情况，取得较好结果，现报告如下。1材料和方法1．1临床标本经病理确诊、手术切除的上消化道肿瘤标本42例，其中食管鳞癌19例、贲门癌9例、胃腺癌13例，经福尔马
We used the digoxigenin-labeled c-erbB-2 and c-my cDNA probes to detect the amplification of two oncogenes in upper digestive tract tumors using in situ hybridization. The results are as follows: . 1Materials and methods 1.1 Clinical specimens of 42 cases of upper digestive tract tumors confirmed by pathology were surgically removed, including 19 cases of esophageal squamous cell carcinoma, 9 cases of cardiac cancer, and 13 cases of gastric adenocarcinoma.