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作者于1992年在泰国曼谷选择了131例16—60岁症状和临床体征相似的急性单纯性恶性疟患者,进行了一项口服蒿甲醚或联用甲氟喹治疗的随机试验。 受试患者分成三个治疗组,第一组38例,采用5天疗法,即首剂服蒿甲醚100mg,之后每12小时服50mg,连服5天,总量500mg;第二组49例,为7天疗法,即首剂服蒿甲醚100mg,后每12小时服50mg,连服7
In 1992, the authors selected 131 patients with acute simplex falciparum malaria who had symptoms and clinical signs ranging from 16 to 60 years of age in Bangkok, Thailand, and conducted a randomized trial of oral artemether or mefloquine. The patients were divided into three treatment groups, the first group of 38 patients, using 5 days therapy, that is, the first dose of artemether 100mg, after every 12 hours serving 50mg, even for 5 days, the total amount of 500mg; the second group of 49 patients , 7 days therapy, that is, the first dose of artemether 100mg, after every 12 hours serving 50mg, and even served 7