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临床常用的四环素类药物有金霉素、土霉素、四环素。近年来又先后半合成一些效力更强的去甲金霉素、甲烯土霉素、强力霉素、二甲胺四环素等等。它们有共同的菲烷结构主核,仅在5、6、7位上取代基有所不同。其基本结构式如下:
Commonly used tetracycline drugs are chlortetracycline, oxytetracycline, tetracycline. In recent years, it has semi-synthesized a number of more effective dementia, methacycline, doxycycline, minocycline, and so on. They have a common main structure of the diketone core, only in the 5,6,7 position on the different substituents. The basic structural formula is as follows: