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目的:观察通天口服液辅助治疗急性脑梗死的临床效果。方法:选择急性脑梗死96例,随机分为观察组与对照组各48例。对照组给予抗血小板聚集、降压、降脂、控制血糖等基础治疗,观察组在此基础上加用通天口服液治疗。疗程均为14天,比较两组美国国立卫生研究院卒中量表(NIHSS)评分、格拉斯哥(Glasgow)昏迷评分、血液流变学参数变化,以及治疗后改良Rankin量表评分。结果:两组NIHSS评分分值均较治疗前显著降低(P<0.05),观察组NIHSS评分分值显著低于对照组(P<0.05);两组Glasgow昏迷评分分值均较治疗前显著升高(P<0.05),观察组Glasgow昏迷评分分值显著高于对照组(P<0.05)。治疗后,观察组高切黏度、低切粘度、血浆黏度及血细胞比容均显著低于对照组(P<0.05)。结论:通天口服液辅助治疗可提高急性脑梗死治疗效果,改善患者血黏度。
Objective: To observe the clinical effect of Tongtian Oral Liquid in the treatment of acute cerebral infarction. Methods: A total of 96 acute cerebral infarction patients were randomly divided into observation group and control group with 48 cases each. Control group given anti-platelet aggregation, blood pressure, lipid-lowering, blood glucose control and other basic treatment, the observation group on the basis of Tongtou oral solution therapy. The duration of treatment was 14 days. The NIHSS score, Glasgow coma scale, hemorheological parameters and post-treatment modified Rankin scale were compared between the two groups. Results: NIHSS scores of both groups were significantly lower than those before treatment (P <0.05), and NIHSS scores of the observation group were significantly lower than those of the control group (P <0.05). Glasgow coma score scores of both groups were significantly higher than those before treatment (P <0.05). The Glasgow coma score in the observation group was significantly higher than that in the control group (P <0.05). After treatment, the high shear viscosity, low shear viscosity, plasma viscosity and hematocrit in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: Tongtian oral liquid adjuvant therapy can improve the therapeutic effect of acute cerebral infarction and improve the blood viscosity of patients.