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由于牙科医生在诊治中接触患者的血液,因此HCV感染的危险性很高.本文报道纽约市牙科医生中职业性HCV感染的危险性.受试者为1986年10月至1987年5月参与一项HIV职业性感染研究中的牙科医生,目前或既往均无静注毒品成瘾、同性恋或异性恋史.459例受试者中456例的血清曾行HCV检测.对照组723例选自1985年3月至1986年4月纽约血液中心的供血员,不包括有同性或异性恋、静注毒品成瘾及肝炎史者.所有血清标本均用放射免疫法检测抗-HBs.用ELISA检测抗-HCV,对多次ELISA检测阳性的标本再用重组免疫印迹法验证.
The risk of HCV infection is high due to the dentist’s exposure to the patient’s blood during diagnosis and treatment.This article reports on the risk of occupational HCV infection among dentists in New York City.The subjects participated in a cohort of patients from October 1986 to May 1987 Dentists in the study of HIV occupational infections had no current or past history of drug addiction, homosexuality, or heterosexuality, 456 of the 459 subjects had an HCV test, and 723 of the control group were selected from 1985 Blood donors from the New York Blood Center from March to April 1986, excluding homosexual or heterosexual, intravenous drug addiction and hepatitis history, all anti-HBs were detected by radioimmunoassay in all serum samples. -HCV, multiple positive ELISA test specimens and then using recombinant immunoblotting validation.