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检测了５２例正常人和１１０例急性白血病患者血清β２微球蛋白含量，正常人为１．７４±０．６５ｍｇ／Ｌ，急性白血病患者为２．９４±１．２０ｍｇ／Ｌ。两者之间有显著差异（ｔ＝６．８８，Ｐ＜０．０１）。急性淋巴细胞白血病β２微球蛋白为３．１８±１．２８ｍｇ／Ｌ，急性非淋巴细胞白血病为２．６６±０．９１ｍｇ／Ｌ，前者高于后者（ｔ＝４．８５，Ｐ＜０．０１）。急性淋巴细胞白血病β２微球蛋白含量与白血病细胞浸润程度有关，而急性非淋巴细胞白血病各亚型之间也有一定差异。因而，检测β２微球蛋白含量对诊断、鉴别诊断、病情估计、疗效观察，急性非淋巴细胞白血病分型，均有一定意义。
Serum β2-microglobulin levels were measured in 52 normal subjects and 110 acute leukemia patients, with a normal population of 1.74 ± 0.65 mg / L and acute leukemia patients of 2.94 ± 1.20 mg / L. There was a significant difference between the two (t = 6.88, P <0.01). The acute lymphoblastic leukemia β2 microglobulin was 3.18 ± 1.28mg / L, acute non-lymphocytic leukemia was 2.66 ± 0.91mg / L, the former is higher than the latter (t = 4.85, P <0 .01). Acute lymphoblastic leukemia β2 microglobulin content and the degree of leukemia cell infiltration, and acute non-lymphocytic leukemia subtypes are also some differences. Therefore, the detection of β2 microglobulin content for diagnosis, differential diagnosis, disease estimation, efficacy observation, acute non-lymphocytic leukemia typing, have some significance.