许多肥胖者都会有一种堪称“病态”的饥饿感,他们不仅会过量进食,且对高热量食物“情有独钟”。之所以会这样,被认为是他们体内FTO基因变异所致,但具体机制则一直不明。一国际研究小组在最新一期《临床研究期刊》上发表论文称,他们研究发现,FTO基因变异会导致体内胃饥饿素水平增高,并改变大脑对胃饥饿素的反应方式和食物的印象,从而导致肥胖者“胃口大开”。 Many obese people have a sense of hunger called “morbid” who not only eat too much but also “have a special appetite for high-calorie foods.” The reason why this is believed to be caused by mutations in the FTO gene in their body, but the specific mechanism has not been clear. An international team published a paper in the latest issue of the Journal of Clinical Research saying they found that mutations in the FTO gene lead to increased levels of ghrelin in the body and alter the brain’s response to ghrelin and food impressions, Cause obesity “appetite ”.