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淋巴瘤通过放化疗可获得很高的治愈率。治疗过程中,疗效评估对于评价或调整治疗方案至关重要。基于病灶形态学改变的传统影像学技术如计算机断层扫描(computed tomography,CT)与磁共振成像(magnetic resonance imaging,MRI)技术在评估淋巴瘤疗效时存在一定的局限性;磁共振加权成像(diffusion-weighted imaging,DWI)结合水分子表观弥散系数(apparent diffusion coefficient,ADC)从分子水平反映疾病的病理生理状态,是一种功能成像新技术;而正电子发射断层显像/X线计算机体层成像(Positron emission tomography/computed tomography,PET/CT)将肿瘤的代谢与形态相结合,是一种新型的功能成像技术,已广泛应用于淋巴瘤患者的分期、疗效监测和预后评估中,可较其他影像学技术更准确的评估疗效;PET/MRI技术在淋巴瘤方面的临床应用研究目前尚处于初步阶段,其临床价值尚需进一步探讨。
Lymphoma by radiotherapy and chemotherapy can get a high cure rate. In the course of treatment, the evaluation of the effect is important for evaluating or adjusting the treatment plan. Traditional imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) based on morphological changes of the lesion have some limitations in assessing the therapeutic effect of lymphoma. Magnetic resonance weighted imaging -weighted imaging (DWI) is a new functional imaging technique combined with the apparent diffusion coefficient (ADC) of water molecules to reflect the pathophysiological state of the disease at the molecular level. However, positron emission tomography / X-ray computed body Positron emission tomography / computed tomography (PET / CT) is a new functional imaging technique combining the metabolism and morphological features of the tumor. It has been widely used in the staging, curative effect monitoring and prognosis evaluation of patients with lymphoma More accurate than other imaging techniques to assess the efficacy; PET / MRI in lymphoma clinical research is still in its infancy, its clinical value needs further study.