本文研究了牛胆酸钠(TC-Na)和牛去氧胆酸钠(TDC-Na)促进亲水性小分子和大分子化合物在离体兔角膜的渗透作用。作者选用6-羧基荧光素(CF)和谷胱甘肽(GSH)作为亲水性小分子化合物,FITC-右旋糖酐(分子量4000)和胰岛素(分子量5500)作为大分子化合物。GSH、CF、FITC-右旋糖酐和胰岛素均用等渗缓冲液分别制成2%w/w、0.05%w/w、0.05%w/w和1 U/ml In this paper, the effects of sodium taurocholate (TC-Na) and sodium deoxycholate (TDC-Na) on the permeation of hydrophilic small molecules and macromolecular compounds in rabbit cornea were studied. The authors selected 6-carboxyfluorescein (CF) and glutathione (GSH) as hydrophilic small molecule compounds, FITC-dextran (molecular weight 4000) and insulin (molecular weight 5500) as macromolecular compounds. GSH, CF, FITC-dextran, and insulin were made into 2% w / w, 0.05% w / w, 0.05% w / w and 1 U / ml