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目的探讨药学服务对慢性心力衰竭患者应用他汀类药物依从性的干预效果。方法 140例应用他汀类药物进行治疗的慢性心力衰竭患者,随机分观察组和对照组,各70例。对照组患者门诊药房在调配药品时随机进行用药指导,观察组患者建立其健康档案,定期进行电话随访,实施药学服务。(实施健康教育、指导他汀类药物应用、进行心理疏导、加强与临床联系)观察两组患者的依从性。结果随访3个月~3年,平均随访(1.42±0.31)年;观察组相关知识掌握为92.86%、他汀类药物依从性好为88.57%,均明显高于对照组的71.43%、68.57%(P<0.05)。随访期间住院(1.35±0.27)次,总住院时间(25.26±7.34)d,低于对照组的(2.34±0.45)次、(34.38±8.39)d,差异具有统计学有意义(P<0.05)。结论对门诊慢性心力衰竭应用他汀药物的患者实施药学干预,扩展了医院外延功能,有助于患者提高健康的认识,增强遵医行为,减少病情复发,推进合理应用他汀药物,值得临床应用。
Objective To investigate the effect of pharmacological intervention on statin compliance in patients with chronic heart failure. Methods 140 cases of chronic heart failure patients treated with statins were randomly divided into observation group and control group, 70 cases in each. Outpatient pharmacies in the control group were randomly assigned medication guidance, observation group patients to establish their health records, regular telephone follow-up, the implementation of pharmaceutical services. (Implementing health education, guiding the use of statins, psychological counseling, and strengthening clinical contact) to observe the compliance of the two groups of patients. The results were followed up for 3 months to 3 years, with an average follow-up of (1.42 ± 0.31) years. The observation group had a knowledge of 92.86% and statin compliance was 88.57%, significantly higher than 71.43% and 68.57% of the control group P <0.05). The difference was statistically significant (P <0.05). The difference was statistically significant (1.35 ± 0.27), total hospital stay (25.26 ± 7.34) d, lower than the control group (2.34 ± 0.45) and (34.38 ± 8.39) . Conclusion The implementation of pharmacy intervention in patients with chronic heart failure outpatient service of statins, expand the hospital’s extension of function, help patients to improve their health awareness, enhance compliance behavior, reduce the recurrence of disease, promote the rational use of statins, worthy of clinical application.