降钙素基因相关肽(calcitonin Gene-Relatedpeptide,CGRP)广泛分布于心血管系统,是目前已知最强的血管舒张剂。我们曾报告,自发性高血压大鼠的腹主动脉内的CGRP含量明显升高,而血浆CGRP水平显著降低,提示CGRP的释放障碍可能是引起高血压的因素之一。应用CGRP可使自发性高 Calcitonin gene-related peptide (calcitonin Gene-Related peptide, CGRP) is widely distributed in the cardiovascular system, is currently the strongest known vasodilator. We have reported that the content of CGRP in the abdominal aorta of spontaneously hypertensive rats was significantly increased, while the level of plasma CGRP was significantly decreased, suggesting that the release of CGRP may be one of the factors that cause hypertension. Application of CGRP can make spontaneity high