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吸入戌烷眯已经成为预防和治疗间质性浆细胞性肺炎的主要方法,通过喷出量和雾滴的大小来比较四种喷雾器(Acorn—22,Znspiron,Cirrus,RespirgardⅡ)的效能,还有一种超声喷雾器(Fisoneb),具有两倍的戍烷眯浓度和3倍的流动速率,因为使用了激光粒子分类器.除Respirgard Ⅱ系统之外,在所有情况下,雾滴的大小(物粒直径在1.2～4.7μm)都是决定于驱动设备的气体流速和所用的成烷脒的浓度.药物的喷出量因不同的喷雾器而自显著差别,以300mg的戌烷脒为例:Acorn—22为61%,Znspiron为62%,Fisoneb为49%,ResspirgardⅡ为43%.雾滴的大小和药物喷出量都是测定喷雾器效能的重要因素.
Inhalation of decane has become the main method for the prevention and treatment of interstitial plasma cell pneumonia. The efficacy of four sprayers (Acorn-22, Znspiron, Cirrus, RespirgardII) is compared by the amount of spray and the size of droplets. An ultrasonic atomizer (Fisoneb), which has twice the decane concentration and 3 times the flow rate, because of the use of laser particle classifiers. In all cases except the Respirgard II system, the droplet size (grain diameter) In the range of 1.2 to 4.7 μm), the flow rate of the gas for the driving device and the concentration of the alkylating agent used are determined. The amount of drug ejected differs significantly depending on the sprayer. Take 300 mg of decane as an example: Acorn-22 It was 61%, Znspiron was 62%, Fisoneb was 49%, and ResspirgardII was 43%. The size of the droplet and the amount of drug that was ejected were all important factors in determining the effectiveness of the nebulizer.