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目的:观察补虚化瘀汤联合西药治疗不稳定型心绞痛的临床疗效。方法:将64例患者随机分为治疗组与对照组,均予西医常规治疗,治疗组加用补虚化瘀汤。观察两组患者治疗前后临床症状、心电图、血液流变学、血清总胆固醇(TC)、甘油三酯(TG)的变化。结果:心绞痛疗效判定:治疗组总有效率为94.8%,对照组为72%,治疗组优于对照组(P<0.05);在减少心绞痛发作次数、持续时间和心电图缺血性改变方面,治疗组明显优于对照组(P<0.05);在调节血脂代谢方面,两组治疗后TC、TG较治疗前均明显下降(P<0.05),治疗组优于对照组(P<0.05);在改善血浆粘度方面,治疗组优于对照组(P<0.05)。结论:补虚化瘀汤联合西药治疗不稳定心绞痛疗效显著。
Objective: To observe the clinical efficacy of Buxuhuayu decoction combined with Western medicine in the treatment of unstable angina pectoris. Methods: Sixty-four patients were randomly divided into treatment group and control group, both of which were treated routinely with Western medicine. The treatment group was treated with Buxuhuayu decoction. The changes of clinical symptoms, electrocardiogram, hemorheology, serum total cholesterol (TC) and triglyceride (TG) in two groups before and after treatment were observed. Results: The curative effect of angina pectoris was found in 94.8% of the patients in the treatment group and 72% in the control group, which was better than that of the control group (P <0.05); in terms of reducing the number of angina attacks, the duration and ischemic changes of ECG, (P <0.05). Compared with the control group, the levels of TC and TG in the two groups were significantly decreased (P <0.05), while those in the treatment group were better than those in the control group (P <0.05) In terms of improving plasma viscosity, the treatment group was better than the control group (P <0.05). Conclusion: Buxuhuayu decoction combined with western medicine has obvious curative effect on unstable angina pectoris.