论文部分内容阅读
目的探析在糖尿病性视网膜病变及肾病治疗中采取羟苯磺酸钙胶囊联合复方丹参滴丸的临床效果。方法 120例糖尿病性视网膜病变及肾病患者,据治疗方式的不同分为参照组与实验组,各60例。参照组采取复方丹参滴丸单独治疗,实验组采取复方丹参滴丸联合羟苯磺酸钙胶囊治疗。比较两组患者的临床疗效。结果实验组总有效率98.33%高于参照组83.33%,差异具有统计学意义(χ~2=8.1068,P<0.05)。治疗后,实验组患者尿蛋白(144.23±5.23)mg/24 h、血尿素氮(6.12±0.56)mmol/L、血肌酐(101.23±3.25)mmol/L,参照组患者尿蛋白(179.68±4.02)mg/24 h、血尿素氮(6.98±0.34)mmol/L、血肌酐(141.39±3.87)mmol/L,实验组尿蛋白、血尿素氮、血肌酐水平均低于参照组,差异均具有统计学意义(t=41.6276、10.1682、61.5551,P<0.05)。结论将复方丹参滴丸联合羟苯磺酸钙胶囊疗法应用在糖尿病性视网膜病变以及肾病治疗中效果显著,可以改善患者生存质量,值得广泛推广应用。
Objective To investigate the clinical effect of taking calcium dobesilate combined with compound Danshen dripping pills in the treatment of diabetic retinopathy and nephropathy. Methods 120 patients with diabetic retinopathy and nephropathy patients were divided into reference group and experimental group according to the different treatment methods, each 60 cases. The reference group take compound Danshen dripping pills alone, the experimental group to take compound Danshen dripping pills combined with calcium dobesilate. The clinical efficacy of the two groups was compared. Results The total effective rate in the experimental group was 98.33% higher than that in the reference group (83.33%), the difference was statistically significant (χ ~ 2 = 8.1068, P <0.05). After treatment, urinary protein (144.23 ± 5.23) mg / 24 h, blood urea nitrogen (6.12 ± 0.56) mmol / L, serum creatinine (101.23 ± 3.25) mmol / L and urine protein of the reference group (179.68 ± 4.02 (mg / 24 h), blood urea nitrogen (6.98 ± 0.34) mmol / L and serum creatinine (141.39 ± 3.87) mmol / L respectively.The levels of urinary protein, blood urea nitrogen and serum creatinine in the experimental group were lower than those in the reference group Statistical significance (t = 41.6276, 10.1682, 61.5551, P <0.05). Conclusion The application of compound Danshen dripping pills and calcium dobesilate capsules in the treatment of diabetic retinopathy and nephropathy has significant effect, which can improve the quality of life of patients and deserves wide application.