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目的探讨支气管肺泡灌洗液(BAL)和纤维支气管镜刷片在肺癌诊断的作用。方法对天津市海河医院27例疑为肺癌并进行了纤维支气管镜检查患者的细胞病理学特征进行分析和评价。结果 27例患者中,组织学确诊肺癌11例(40.74%),其中包括鳞状低胞癌8例(72.73%),腺癌2例(18.18%),小细胞肺癌1例(9.09%);纤维支气管镜刷片的敏感性为45.45%,特异性为87.50%;灌洗液敏感性为36.36%,特异性为93.75%。两者准确率相同,70.37%。结论在肺癌的诊断中支气管肺泡灌洗液BAL及纤维支气管镜刷片细胞病理学检查,但缺少良好的敏感性具有相对较高的特异性。
Objective To investigate the role of bronchoalveolar lavage fluid (BAL) and fiberoptic bronchoscope in the diagnosis of lung cancer. Methods The cytopathological features of 27 patients suspected of lung cancer who underwent fibrobronchoscopy in Haihe Hospital of Tianjin were analyzed and evaluated. Results Among the 27 patients, 11 cases (40.74%) had lung cancer confirmed by histology, including 8 cases of squamous cell carcinoma (72.73%), 2 cases of adenocarcinoma (18.18%) and 1 case of small cell lung cancer (9.09%). The sensitivity of bronchoscopic brush was 45.45% and the specificity was 87.50%. The sensitivity of perfusion fluid was 36.36% and the specificity was 93.75%. The same accuracy rate of both, 70.37%. Conclusions Cytopathology examination of bronchoalveolar lavage (BAL) and bronchoscopic brush was used in the diagnosis of lung cancer, but the lack of good sensitivity was relatively high specificity.