近期已应用人体内分泌腺组织免疫小鼠,使生成相应的单克隆抗体,再从中进一步研究该内分泌细胞的病理生理学和组织病理学.鉴于中肠类癌肿瘤源自远端十二指肠至远端横结肠的粘膜内分泌细胞,除了阑尾类癌外这些肿瘤易转移,作者进行这方面单克隆抗体的探索以求改进其组织病理学诊断、肿瘤定位和治疗效果. Recently, human endocrine glands have been used to immunize mice to produce the corresponding monoclonal antibodies, and further to study the pathophysiology and histopathology of the endocrine cells. In view of the midgut carcinoid tumors originating from the distal duodenum to the far The mucosal endocrine cells of the transverse colon, in addition to appendix carcinoids, these tumors are easy to metastasize, the authors explored monoclonal antibodies in this area in order to improve its histopathological diagnosis, tumor localization and therapeutic effect.