论文部分内容阅读
目的探讨小儿喘息型支气管炎采用吸入用硫酸沙丁胺醇溶液(万托林)及吸入用布地奈德混悬液(普米克令舒)雾化吸入联合治疗的效果。方法 68例小儿喘息型支气管炎患儿,随机分为对照组和治疗组,各34例。对照组给予常规治疗,治疗组给予常规措施+万托林及普米克令舒雾化吸入联合治疗,两组均连续治疗7 d,观察两组临床疗效。结果治疗组治疗总有效率为94.1%高于对照组的76.5%,差异有统计学意义(P<0.05)。治疗组湿啰音、哮鸣音、咳嗽、三凹征、憋喘缓解时间及住院时间均显著短于对照组,差异有统计学意义(P<0.05)。治疗前,两组血清白介素4(IL-4)和干扰素γ(IFN-γ)水平比较,差异无统计学意义(P>0.05);治疗后,治疗组血清IFN-γ水平显著升高,且高于对照组,血清IL-4水平显著下降,且低于对照组,差异有统计学意义(P<0.05)。结论小儿喘息型支气管炎采用万托林及普米克令舒雾化吸入联合治疗,安全性较高,且疗效显著,具有推广价值。
Objective To investigate the effect of inhalation combined with inhalation of budesonide sulfate solution (Vtopine) and inhalation of budesonide suspension (pulmicort respules) by atomization inhalation in children with asthmatic bronchitis. Methods Sixty-eight children with asthmatic bronchitis were randomly divided into control group and treatment group, 34 cases in each group. The control group was given routine treatment, and the treatment group was given conventional measures combined with wantroplin and pulmicort respiration inhalation. Both groups were treated for 7 consecutive days and the clinical efficacy was observed. Results The total effective rate of treatment group was 94.1% higher than 76.5% of control group, the difference was statistically significant (P <0.05). The treatment group, the wet rale, wheeze, cough, three concave sign, hold in relief time and hospital stay were significantly shorter than the control group, the difference was statistically significant (P <0.05). Before treatment, serum interleukin-4 (IL-4) and interferon-γ (IFN-γ) levels were not significantly different between the two groups (P> 0.05); after treatment, serum IFN- And higher than the control group, serum IL-4 levels decreased significantly, and lower than the control group, the difference was statistically significant (P <0.05). Conclusion Pediatric wheezing bronchitis with Wan Tolrine and Pulmicort Respiratory inhalation combination therapy, high safety, and significant effect, with the promotion of value.