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目前国内多运用白酒灌胃及酒精腹腔注射的方法制作急性酒精性肝损伤模型,但造模时间报道不一。笔者运用红星牌二锅头酒(56度)给大鼠灌胃5天造成大鼠急性酒精性肝损伤模型,取材方便,易于操作,引起的病理改变类似于人类酒精性肝损伤。现报道如下。材料与方法1·实验动物Wistar大
At present, the domestic use of liquor and alcohol intraperitoneal injection method to make acute alcoholic liver injury model, but modeling time reported differently. The author uses Red Star brand Erguotou wine (56 degrees) to rats for 5 days gavage rat model of acute alcoholic liver injury, easy access, easy to operate, caused by pathological changes similar to human alcoholic liver injury. Report as follows now. Materials and Methods 1. Experimental animals Wistar large