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现今耐药性基因型检测法成为HIV控制领域普遍关注的问题。虽然已经公布了清晰的应用指南来引导恰当地使用这些检测法,临床医生和科学家们仍然努力想要在有限的预算和时间的约束下决定HIV耐药性检测的最优用法。这篇文章主要针对一些实际的临床案例展开讨论,其目标是为了深入了解何时、何处能够将耐药基因型检测最有效地应用于HIV阳性成人患者。
Today’s drug resistance genotyping has become a common concern in the area of HIV control. Although clear guidelines have been published to guide the proper use of these assays, clinicians and scientists are still struggling to determine the optimal use of HIV drug resistance testing with limited budget and time constraints. This article focuses on a few real-world clinical cases and aims to gain insight into when and where genotyping of resistant strains can be most effectively applied to HIV-positive adults.