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报道1例因重症肌无力接受免疫球蛋白静脉注射(IVIG)而发生双侧脑血栓形成者。病人女性,27岁,血压正常,患重症肌无力3年。因构语障碍,周身肌肉无力和易疲劳而住院,予呲啶斯的明90mg每4小时一次口服,强的松60mg/d和硫唑嘌呤125mg(2.5mg/kg)/d治疗。其胸腺已在确诊重症肌无力后第一年被切除。因血浆换出法疗法无效而改用(intravenous immunoglobulin IVIG)(400mg/kg/d)。第4次IVIG注射后,病人发生严重搏动性头痛、恶心、呕吐、体温高达101.9~°F。头部CT正常,脑脊液白细胞41/mm~3,VDRL阴性。脑脊液特殊染色及细菌培养未发现异常。 IVIG治疗后10天,除仍有头痛外,尚发生了
Reported in 1 case of myasthenia gravis received intravenous immunoglobulin (IVIG) occurred in patients with bilateral cerebral thrombosis. Patient Female, 27 years old, with normal blood pressure and 3 years of myasthenia gravis. For constitutional disorders, whole body muscle weakness and fatigue and hospitalization, to the Blend of 90mg every 4 hours once oral, prednisone 60mg / d and azathioprine 125mg (2.5mg / kg) / d treatment. The thymus has been diagnosed in the first year after myasthenia gravis was removed. Reversal of intravenous immunoglobulin IVIG (400 mg / kg / d) due to ineffective plasma exchange therapy. After the IV IV injection, the patient developed severe pulsatile headache with nausea and vomiting, with body temperature as high as 101.9 ° F. Head CT normal, cerebrospinal fluid leukocyte 41 / mm ~ 3, VDRL negative. Cerebrospinal fluid special staining and bacterial culture found no abnormalities. Ten days after IVIG treatment, except for headaches, it still happened