动脉粥样硬化斑块破裂和伴随血栓形成是急性冠状动脉综合征(acute coronary syndrome,ACS)的主要病理基础和发病机制,研究证实不稳定斑块局部有大量中性粒细胞和巨噬细胞的浸润及炎症因子的表达.炎症在动脉粥样硬化中起着重要的作用,而炎症介质参与粥样斑块形成至最终破裂整个过 Atherosclerotic plaque rupture and accompanying thrombosis are the main pathological basis and pathogenesis of acute coronary syndrome (ACS). Studies have shown that there are a large number of neutrophils and macrophages in the unstable plaque Infiltration and expression of inflammatory cytokines Inflammation plays an important role in atherosclerosis while the inflammatory mediators are involved in the formation of atherosclerotic plaque until the eventual rupture has occurred