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本文研究了不同离子半径稀土族核素的体内滞留特性和诱发体细胞突变效应的比较。发现不同稀土族核素离子半径的大小,对其在选择性滞留器官中的分布有重要作用:在肝中的蓄积,可随离子半径的增大而增多;在骨中的蓄积正相反,可随离子半径的减小而增多。离子半径不同的稀土族核素诱发骨髓细胞突变效应的程度,可随骨组织中累积滞留量的增加而相应升高,并可导致在一个细胞中有多个畸变发生,而形成多畸变细胞的程度以~(147)Pm为最高,其后依次为~(152)Eu和~(170)Tm。
In this paper, we studied the in vivo retention characteristics and somatic mutation effects of different ion radius rare earth nuclides. It is found that the ionic radii of different rare earth nuclides play an important role in the distribution of selective retention organs: the accumulation in the liver may increase with the increase of ion radius; the accumulation in the bone is the opposite and With the decrease of ion radius increased. Rare earth nuclides with different ion radii can induce the mutation effect of myeloid cells, which may increase with the increase of accumulated retention in bone tissue and lead to multiple aberrations in one cell, and the formation of multi-aberrant cells The highest level is ~ (147) Pm, followed by ~ (152) Eu and ~ (170) Tm.