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对52例口服磺脲类降糖药无效的T2DM的患者分别采用甘舒霖30R联合二甲双胍和单独甘舒霖30R治疗4周后,FPG,2hPG,以及用量和不良反应。结果:治疗组FPG6.56±1.68 mmol/L,2hPG10.41±2.2 mmol/L,有效率68.75%,较治疗前下降有显著性。与对照组比,P﹥0.05,但甘舒霖30R有效维持用量:治疗组29.52±8.2Iu/d,对照组39.3±8.6Iu/d。两组比较P﹤0.01。结论联合对治疗继发性磺脲类治疗失效的病人有较好疗效,外源性胰岛素较对照组节约24.9%。P﹤0.01。
Fifty-two patients with T2DM who did not receive oral hypoglycemic agents were treated with Gansuolin 30R plus metformin and Gannan Gansu 30R for 4 weeks, FPG, 2hPG, and dosage and adverse reactions respectively. Results: The treatment group FPG6.56 ± 1.68 mmol / L, 2hPG10.41 ± 2.2 mmol / L, the effective rate was 68.75%, compared with before treatment decreased significantly. Compared with the control group, P> 0.05, but Gan Shu Lin 30R effective maintenance dose: the treatment group 29.52 ± 8.2Iu / d, the control group 39.3 ± 8.6Iu / d. The two groups compared P <0.01. Conclusion Combined treatment of secondary sulfonylurea treatment failure patients have a good effect, exogenous insulin than the control group, saving 24.9%. P <0.01.