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接种乙型肝炎疫苗,不一定都产生HBs抗体,而且有人由于反应极低,在免疫过程中,却成了病毒携带者.本文为了研究这种HBs抗体产生不全状态与HLA的关系,分别检查了接种乙型肝炎疫苗小儿的HLA-A、B、C及DR基因位点.作者以观察一年以上的HBs抗原及HSe抗原阳性孕妇所生、采取了预防垂直感染措施的97例小儿为观察对象.小儿生后48小时内,静注乙肝免疫球蛋白(HBIG)及肌注HBIG,或单独肌注HBIG进行初次被动免疫,以达到预防分娩时HBV感染的目的.对达到预防感染效果的小儿,在生后第
Inoculation of hepatitis B vaccine, not necessarily produce HBs antibodies, and some people because of the reaction is very low, in the immune process, but became a virus carrier.In order to study the relationship between HBs antibody production status and HLA, were examined HLA-A, B, C and DR gene loci in children vaccinated with hepatitis B. The authors observed 97 children with HBs antigen and HSe antigen-positive pregnant women who had been observed for more than one year and took vertical infection prevention measures In 48 hours after birth, hepatitis B immunoglobulin (HBIG) and intramuscular injection of HBIG, or intramuscular injection of HBIG alone for the first time during passive immunization in order to achieve the purpose of preventing HBV infection during childbirth.To achieve the effect of preventing infection in children, After birth