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目的探析多西他赛化疗联合放疗治疗食管癌的临床疗效。方法 50例接受非手术治疗的食管癌患者,随机分为观察组和干预组,各25例。观察组患者给予常规的放疗方式,干预组患者在观察组患者基础上行多西他赛化疗。对比两组患者采用治疗方式的临床有效性。结果两组患者的临床总有效率对比,干预组(92.0%)明显优于观察组(72.0%),差异具有统计学意义(P<0.05);两组患者治疗后的不良反应对比,观察组的发生率为44.0%,干预组为40.0%,两组差异无统计学意义(P>0.05)。结论给予食管癌患者采用多西他赛化疗联合放疗治疗的效果相比单纯的放疗效果较佳,值得在临床中推广应用。
Objective To investigate the clinical efficacy of docetaxel chemotherapy combined with radiotherapy in the treatment of esophageal cancer. Methods Fifty patients with esophageal cancer who underwent nonsurgical treatment were randomly divided into observation group and intervention group, with 25 cases in each group. Patients in the observation group were given conventional radiotherapy. Patients in the intervention group received docetaxel chemotherapy on the basis of the observation group. The clinical efficacy of the treatment was compared between the two groups. Results The total effective rate of the two groups was significantly higher than that of the observation group (92.0%) (72.0%), the difference was statistically significant (P <0.05); the adverse reactions of the two groups after treatment were significantly lower than those of the observation group The incidence was 44.0% in the intervention group and 40.0% in the intervention group, with no significant difference between the two groups (P> 0.05). Conclusions The effect of docetaxel chemotherapy combined with radiotherapy for patients with esophageal cancer is better than that of radiotherapy alone and is worth popularizing in clinic.