目的　研究美洛昔康 (meloxicam ,简称MLX)的电化学行为和电极反应机理 ,拟定了测定MLX的吸附伏安法。方法　用单扫示波极谱法、循环伏安法和脉冲极谱法等多种技术进行研究。结果　在HAc NaAc(pH 4 76 )底液中 ,MLX在汞电极上有一线性扫描还原峰 ,峰电位Ep=- 1 19V(vsAg/AgCl) ,该峰有明显的吸附性。吸附粒子为MLX中性分子 ,测得MLX在汞电极上的饱和吸附量为 1 5 3× 10 -10 mol·cm-2 ,每个MLX分子所占电极面积为 1 0 8nm2 ,MLX在悬汞电极上的吸附符合Frumkin等温式。测得吸附系数 β =1 6 5× 10 6,电子转移数 (n)为 2 ,不可逆吸附的电子转移系数 (α)为 0 84,表面电极反应的速率常数ks=0 19·s-1。建立了吸附伏安法测定MLX的最佳条件 ,检出限为 1 0× 10 -9mol·L-1。结论　证实该体系为具有吸附性的不可逆过程 Aim To study the electrochemical behavior and electrode reaction mechanism of meloxicam (MLX), and to determine the adsorption voltammetry of MLX. Methods Single-sweep oscillopolarography, cyclic voltammetry and pulse polarography and other techniques were studied. Results In HAc NaAc (pH476), MLX showed a linear reduction at mercury electrode with a peak potential of Ep = - 1 19V (vsAg / AgCl). The adsorbed particles were MLX neutral molecules, and the saturated adsorption capacity of MLX on mercury electrode was 15 3 × 10 -10 mol · cm-2. The area of ​​each MLX molecule occupied was 1 0 8 nm 2. The adsorption on the electrode conforms to the Frumkin isotherm. The adsorption coefficient β = 165 × 106, the electron transfer number (n) was 2, the irreversible adsorption electron transfer coefficient (α) was 0 84, and the surface electrode reaction rate constant ks was 0 19 · s -1. The optimal conditions for the determination of MLX by adsorption voltammetry were established. The detection limit was 10 × 10 -9 mol·L-1. The conclusion proves that the system is an irreversible process with adsorption