Expression of reconstructive hFⅧ in the hrDNA by using hrDNA targeting vector

来源 :中国科学通报：英文版 | 被引量 : 0次 | 上传用户：lovewxb1982

【摘要】

：

Our lab has constructed a new nonviral vector-hrDNA targeting vector(pHrneo). pHrneo is a human derived vector that can target gene into human ribosomal DNA(hrD

【作者】

：

LIU Xionghao LIU Mujun SHE Hua

【机构】

：

NationalLabofMedicalGeneticsofChina

【出处】

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中国科学通报：英文版

【发表日期】

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2005年19期

【关键词】

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hrDNA 目标向量人类起源遗传表达核糖体器官重组 human derived vector site-specific integration t

【基金项目】

：

国家重点基础研究发展计划(973计划)，国家高技术研究发展计划(863计划)，国家自然科学基金，湖南省生命科研项目

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Our lab has constructed a new nonviral vector-hrDNA targeting vector(pHrneo). pHrneo is a human derived vector that can target gene into human ribosomal DNA(hrDNA) locus. In this study, we inserted expression cassette of reconstructive hFⅧ (hFVIII-BDDAK39

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Expression of reconstructive hFⅧ in the hrDNA by using hrDNA targeting vector

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