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[目的]观察畅中胶囊合西药治疗消化性溃疡(PU)的临床疗效和2年内的复发率。[方法]对135例PU患者采用随机、对照实验的方法,用中药畅中胶囊加奥美拉唑20 mg,qd,治疗4周,观察临床症状、内镜下的成熟度以及2年内的复发率。[结果]两组症状均有明显减轻,但治疗组临床症状改善显著(P<0.05);内镜下治疗组获得S2期较对照组多(P<0.05);2年内复发率治疗组低于对照组,但差异无统计学意义。[结论]畅中胶囊治疗PU有较好的近、远期疗效。
[Objective] To observe the clinical efficacy of Changzhong Capsule combined with western medicine in treating peptic ulcer (PU) and the recurrence rate in 2 years. [Method] A randomized controlled trial was conducted in 135 patients with PU. The Chinese medicine Changzhong capsule plus omeprazole 20 mg qd for 4 weeks was used to observe clinical symptoms, endoscopic maturation and relapse within 2 years rate. [Results] The symptoms of both groups were significantly reduced, but the clinical symptoms of the treatment group improved significantly (P <0.05). The number of S2 in the treatment group was significantly higher than that in the control group (P <0.05) Control group, but the difference was not statistically significant. [Conclusion] Changzhong Capsule has good short-term and long-term curative effect on PU.