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指南推荐CHA 2 DS-VAS C 评分＞1分的非瓣膜性心房颤动患者长期使用抗凝药物，冠心病进行冠状动脉介入术治疗后，联合使用阿司匹林和P2Y12受体拮抗剂抗血小板至少1年。非瓣膜性心房颤动伴冠心病并接受冠状动脉介入术治疗后如何兼顾抗栓治疗与预防出血风险尚缺乏统一的规范和推荐。现就目前的相关研究做一综述，对进一步的研究提供依据。“,”Clinical guidelines recommended the long-term use of vitamin K antagonists for non-valvular atrial fibrillation patients whose CHA 2 DS-VAS C scores greater than 1.When these patients undergo percutaneous coronary intervention with stenting ,treatment with as-pirin and a P 2 Y 12 receptor inhibitor also becomes indicated .However the methods of ,how to balance the antithrombotic therapy and prevent the risk of bleeding in non-valvular atrial fibrillation patients with coronary heart disease after coronary intervention is still lack of uniform standards and recommendationsed .The aim of this article is to reviews the current new clinical research and provides the basis for the next study.