论文部分内容阅读
目的探讨颈动脉体瘤的临床病理学特点及诊断要点。方法对1例颈动脉体瘤的临床资料、病理形态学及免疫组化特点进行分析,并结合文献对其诊断及鉴别诊断进行探讨。结果本例镜下肿瘤细胞呈巢状条索状生长,间质纤维组织增生,玻璃样变,血窦丰富,中央以主细胞为主,外周以支持细胞为主,瘤细胞胞浆丰富,核圆形、椭圆形,染色质细腻,核分裂象罕见。免疫组化:Syn(+)、Cg A(+)、CD56(+)、S-100(支持细胞+)、EMA(-)、FVIII(+)、AE1/AE3(-)、D2-40(-)、Desmin(-)、Vimentin(+)、CD34(血管+)、GFAP(-)、NSE(+)、Ki-67(index<5%)。结论颈动脉体瘤非常罕见,提高对该病临床病理特点的认识,可避免误诊。
Objective To investigate the clinicopathological features and diagnosis points of carotid body tumor. Methods The clinical data, pathomorphology and immunohistochemical characteristics of one carotid body tumor were analyzed. The diagnosis and differential diagnosis of carotid body tumor were analyzed. Results The tumor cells in this case were nested cord-like growth, interstitial fibrous tissue hyperplasia, glassy change, rich sinusoid, the main central cells to the main supporting cells in the periphery of the main tumor cells rich in cytoplasm, nuclear Round, oval, chromatin delicate, meiosis is rare. Immunohistochemistry: Syn (+), CgA (+), CD56 (+), S-100 (supportive cells +), EMA (-), FVIII (+), AE1 / AE3 -), Desmin (-), Vimentin (+), CD34 (Vascular +), GFAP (-), NSE (+), Ki- 67 (index <5%). Conclusion Carotid body tumor is very rare, to improve the understanding of the clinical and pathological features of the disease, to avoid misdiagnosis.