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目的评估重症急性胰腺炎(severe acute pancreatitis,SAP)患者的远期疗效及健康相关生命质量,分析其影响因素。方法回顾性分析2003年1月至12月出院的98例 SAP 患者相关病历资料,应用 SF-36量表及自制问卷表进行自评式调查,观察其健康相关生命质量及远期疗效。并与普通人群健康相关生命质量进行比较,作相关影响因素的单因素方差分析。自制问卷表单独分析。结果 98例 SAP 患者中,病历资料完整59例,死亡2例,不能完成量表1例,无应答6例,收回有效问卷50例,应答率89.8%。SF-36量表生理功能、生理职能、情感职能、身体疼痛、活力、精神健康、社会功能和总体健康8个维度的得分分别为:(83±15)分、(62±42)分、(69±36)分、(80±15)分、(69±19)分、(72±15)分、(75±18)分和(65±18)分。与普通人群比较,生理职能和社会功能两项与普通人群间差异有统计学意义(P<0.05)。其余6项与普通人群差异无统计学意义(P>0.05)。影响生理健康总分的变量有治疗方式、住院时间、住院费用造成的经济负担。影响心理健康总分的变量有性别和住院费用造成的经济负担。结论 SAP 患者的健康相关生命质量与普通人群相近,远期疗效及生命质量良好,其影响因素主要有性别、治疗方法、住院时间及经济状况。
Objective To evaluate the long-term efficacy and health-related quality of life of patients with severe acute pancreatitis (SAP) and analyze its influencing factors. Methods The clinical data of 98 patients with SAP who were discharged from January 2003 to December 2003 were analyzed retrospectively. The self-rated questionnaires were made using SF-36 scale and self-made questionnaire to observe their health-related quality of life and long-term efficacy. And compared with the health-related quality of life of the general population for single factor analysis of variance. Self-made questionnaire analysis alone. Results Of the 98 patients with SAP, 59 cases were complete with 2 cases of death, 1 case could not be completed, 6 cases did not respond to the questionnaire, and 50 cases were retrieved. The response rate was 89.8%. The scores of physiological function, physiological function, emotional function, body aches, vitality, mental health, social function and overall health of SF-36 scale were (83 ± 15) and (62 ± 42) 69 ± 36, 80 ± 15, 69 ± 19, 72 ± 15, 75 ± 18, and 65 ± 18, respectively. Compared with the general population, there were significant differences in physiological functions and social functions between the two groups and the general population (P <0.05). The remaining 6 items had no significant difference with the general population (P> 0.05). The variables that affect the total score of physical health are the treatment cost, length of hospital stay and cost of hospitalization. The variables that affect the mental health score are the economic burden of gender and hospitalization costs. Conclusion The health-related quality of life of SAP patients is similar to that of the general population. Long-term efficacy and quality of life are good. The main influencing factors are gender, treatment, length of stay and economic status.