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我们应用免疫抑制药物环磷酰胺治疗流行性出血热(60例),获得较好的效果。为了进一步提高疗效,我们又以环磷酰胺加党参、黄芪(45例)和环磷酰胺加干扰素诱导剂聚肌胞(Poly I:C)(21例)治疗流行性出血热。并对部分患者的免疫功能和临床表现进行了观察和疗效比较。治疗后的三组患者其免疫功能即趋恢复,同时临床症状也显著改善。其中环磷酰胺加党参、黄芪和环磷酰胺加 Poly I:C 组的疗效较单用环磷酰胺者为优,且淋转率的回升也较明显;环磷酰胺加 Poly I:C 的退热效果尤较前两组为佳。126例中124例治愈,2例死亡,病纯率1.58%。本文并对治疗的作用进行了讨论。
We use immunosuppressive drugs cyclophosphamide in the treatment of epidemic hemorrhagic fever (60 cases), get better results. To further improve the curative effect, we treated Epidemic Hemorrhagic Fever with cyclophosphamide plus Codonopsis, Astragalus (45 cases) and cyclophosphamide plus Poly I: C interferon inducer (21 cases). And some patients with immune function and clinical manifestations were observed and compared efficacy. Three groups of patients after treatment of immune function is about to recover, while clinical symptoms also significantly improved. Which cyclophosphamide plus Codonopsis, Astragalus and cyclophosphamide plus Poly I: C group compared with single use of cyclophosphamide as excellent, and the turn-over rate was also more obvious; cyclophosphamide plus Poly I: C of the retreat The thermal effect is better than the first two groups. Of the 126 cases, 124 were cured and 2 died, with a disease-free rate of 1.58%. This article also discussed the role of treatment.